Effect of Live Poultry Market Interventions on Influenza A(H7N9) Virus, Guangdong, China
نویسندگان
چکیده
Since March 2013, three waves of human infection with avian influenza A(H7N9) virus have been detected in China. To investigate virus transmission within and across epidemic waves, we used surveillance data and whole-genome analysis of viruses sampled in Guangdong during 2013-2015. We observed a geographic shift of human A(H7N9) infections from the second to the third waves. Live poultry market interventions were undertaken in epicenter cities; however, spatial phylogenetic analysis indicated that the third-wave outbreaks in central Guangdong most likely resulted from local virus persistence rather than introduction from elsewhere. Although the number of clinical cases in humans declined by 35% from the second to the third waves, the genetic diversity of third-wave viruses in Guangdong increased. Our results highlight the epidemic risk to a region reporting comparatively few A(H7N9) cases. Moreover, our results suggest that live-poultry market interventions cannot completely halt A(H7N9) virus persistence and dissemination.
منابع مشابه
Environmental Sampling for Avian Influenza A(H7N9) in Live-Poultry Markets in Guangdong, China
BACKGROUND To provide an increased understanding of avian influenza A(H7N9) activity in live-poultry market in space and time and hence improve H7N9 epidemic control, an ongoing environmental sampling program in multiple live-poultry markets across Guangdong, China was conducted during March 2013-June 2014. METHODS A total of 625 live-poultry markets throughout 21 prefecture areas took part i...
متن کاملThird Wave of Influenza A(H7N9) Virus from Poultry, Guangdong Province, China, 2014–2015
Fourteen influenza A(H7N9) viruses were isolated from poultry or the environment in live poultry markets in Guangdong Province, China during 2014-2015. Phylogenetic analysis showed that all viruses were descended from viruses of the second wave of influenza A(H7N9) virus infections during 2013. These viruses can be divided into 2 branches.
متن کاملPoultry Market Closures and Human Infection with Influenza A(H7N9) Virus, China, 2013–14
Closure of live poultry markets was implemented in areas affected by the influenza virus A(H7N9) outbreak in China during winter, 2013-14. Our analysis showed that closing live poultry markets in the most affected cities of Guangdong and Zhejiang provinces was highly effective in reducing the risk for H7N9 infection in humans.
متن کاملEpidemiology of human infections with highly pathogenic avian influenza A(H7N9) virus in Guangdong, 2016 to 2017
We describe the epidemiology of highly pathogenic avian influenza (HPAI) A(H7N9) based on poultry market environmental surveillance and laboratory-confirmed human cases (n = 9) in Guangdong, China. We also compare the epidemiology between human cases of high- and low-pathogenic avian influenza A(H7N9) (n = 51) in Guangdong. Case fatality and severity were similar. Touching sick or dead poultry ...
متن کاملA8 The epidemiology and evolution of influenza A/H1N1 and A/H3N2 virus from 2010 to 2015, in Ho Chi Minh City, Vietnam
waves have been detected in China. Live poultry market (LPMs) exposure is regarded as a major risk of H7N9 virus infection. However, despite strict interventions implemented in the epicenter cities during each outbreak, reports indicate a gradual nationwide spread of the virus. In this study, the impact of LPMs interventions in virus persistence and transmission in the province of Guangdong, th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 22 شماره
صفحات -
تاریخ انتشار 2016